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The trial enrolled only people with overweight or obesity and no obesity-related illnesses

Over 40 weeks, liraglutide 3.0 mg plus lifestyle modification reduced visceral adipose tissue in adults with overweight or obesity and at high risk of cardiovascular disease (excluding diabetes) compared to placebo (12.5% vs

(3) development of next-generation GLP-1 receptor-targeted therapeutics with enhanced specificity and reduced off-target effects [129,130,131,132]